What can be learned about motoneurone properties from studying firing patterns?
Advances in Experimental Medicine and Biology, vol.508, pp.199-205, 2002 (Scopus)
- Publication Type: Article / Article
- Volume: 508
- Publication Date: 2002
- Doi Number: 10.1007/978-1-4615-0713-0_24
- Journal Name: Advances in Experimental Medicine and Biology
- Journal Indexes: Scopus
- Page Numbers: pp.199-205
- Istanbul Gelisim University Affiliated: No
Abstract
The discharge patterns of tonically-firing neurones are influenced by both the characteristics of their presynaptic input and their intrinsic properties. The regularity of the discharge of motoneurones is thought to reflect their prominent post-spike afterhyperpolarization (AHP). When a motoneurone fires at steady mean rate, the distribution of interspike intervals is determined by the amplitude and frequency content of the synaptic noise together with the decrease in excitability following a spike due to AHP. This paper considers how motoneurone discharge statistics can be used to estimate AHP trajectories as well as a motoneurone's sensitivity to excitatory input.