Ultrasound-assisted rapid synthesis of β-aminoketones with direct-type catalytic Mannich reaction using bismuth(III) triflate in aqueous media at room temperature

Ozturkcan S. A., TURHAN K., TURGUT Z.

Chemical Papers, cilt.66, sa.1, ss.61-66, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2478/s11696-011-0097-z
  • Dergi Adı: Chemical Papers
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.61-66
  • Anahtar Kelimeler: sonochemistry, beta-aminoketones, direct-type Mannich reaction, bismuth(III) triflate, green innovation
  • İstanbul Gelişim Üniversitesi Adresli: Hayır

Özet

An innovative, powerful, efficient and relatively rapid method was developed to synthesise various β-aminoketone derivatives from cyclohexanone, substituted aromatic amines and aromatic or hetero-aromatic aldehydes via ultrasound-assisted direct-type catalytic Mannich reaction using bismuth(III) triflate in water. Good yields of the desired β-aminoketones were obtained at room temperature by ultrasound-assisted reaction within 1-2 h. The major advantages of the proposed method are undemanding conditions, easy operation, low toxicity, shorter reaction time, anti selectivity and higher yields in comparison with conventional methods. © 2011 Institute of Chemistry, Slovak Academy of Sciences.