Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature

Dolanmaz D., Esen A., Mihmanlı A., Işık K.

Oral and Maxillofacial Surgery, cilt.20, sa.2, ss.203-209, 2016 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s10006-015-0530-5
  • Dergi Adı: Oral and Maxillofacial Surgery
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.203-209
  • Anahtar Kelimeler: Corticosteroid, Giant cell granuloma, Intralesional injections, Triamcinolone acetonide
  • İstanbul Gelişim Üniversitesi Adresli: Hayır

Özet

Purpose: We report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws. Methods: Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks. Results: Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage. Conclusions: We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.