Current Diabetes Reviews, cilt.17, sa.5, 2021 (ESCI)
© 2021 Bentham Science Publishers.Background: COVID-19 is a world disaster. The relationship between COVID-19 and Diabetes Mellitus (DM) is double-faced because DM is considered one of the COVID-19 key risk factors causing an increase in COVID-19 related conditions and death rates; at the same time, high stress in patients with COVID-19 can lead to the occurrence of DM. This relationship adversely af-fects immune functions. Relaxation techniques have been demonstrated to positively affect immune functions, glycemic control, and stress levels. Methods: A search in Scopus, Web of Science, Medline databases, and EBSCO has been made. The search included clinical trials and systematic and literature reviews on the effects of relaxation techniques on immune functions, glycemic control, and stress levels. Results: This review found that relaxation techniques produce short-term effects on decreasing stress levels through autonomic regulation, controlling glycemic control through decreasing hyperg-lycemia, and increasing immune functions through increasing immune cells and immunoglobins A. Conclusion: This review summarizes the important role of performing regular relaxation techniques in COVID-19 patients with DM. Relaxation techniques benefit diabetic patients with COVID-19 through decreasing stress levels, better controlling of glycemic control, and increasing immune functions.