Evaluation of gastric inflammatory parameters caused by pyloric ring failure

Üçüncü M. Z., Gürbulak B., Çolak Ş.

Acta Medica Mediterranea, vol.35, no.3, pp.1481-1485, 2019 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.19193/0393-6384_2019_3_229
  • Journal Name: Acta Medica Mediterranea
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1481-1485
  • Keywords: Bile reflux, Failures of pyloric ring, Gastric cancer, Gastric imflammation, Helicobacter pylori, Intestinal metaplasia
  • Istanbul Gelisim University Affiliated: Yes


© 2019 A. CARBONE Editore. All rights reserved.Introduction: We aimed to compare the inflammatory parameters of patients with have failure of pyloric ring with those of that have intact pyloric ring. Material and methods: Patients who underwent upper gastrointestinal endoscopy between May and September 2017 included in this study. The data of the study were collected prospectively and analysed retrospectively. Results: A total of 205 patients were included in this study. 69 (33.7 %) male and 136 (66.3%) female patients, the mean age was 40.1 ± 11.38 years. Endoscopically, failure of pyloric ring was detected in 86 patients and intact pyloric ring in 119 patients. The histopathological examination of antrum; chronic gastritis in 91 patients (44.4 %), active chronic gastritis in 89 patients (44.3%) and normal findings were found in 23 patients (11.2%). The histopathological examination of corpus; chronic gastritis in 105 patients (51.2%), active chronic gastritis in 25 patients (12.2%) and normal findings were found in 73 patients (35.6%). Comparing the patients that have intact and pyloric ring failure, the inflammation and activation scores and Helicobacter Pylori (H. Pylori) density were higher in pyloric ring failure group (p:0.001, p: 0,018, p: 0,006). It was seen that in patients with pyloric ring failure had a significant decrease in inflammatory activation and H. Pylori density toward from antrum to the corpus, and this was statistically significant (p: 0.001, p: 0.001, p: 0.001). Conclusion: Because of the high inflammatory histopathologic parameters caused by pyloric ring failure, these patients should be followed closely.