Akademik Veri Yönetim Sistemi
Türk Kolon ve Rektum Hastalıkları Dergisi, cilt.30, sa.3, ss.184-190, 2020 (TRDizin)
Aim: Post-haemorrhoidectomy pain adversely affects the patients’ comfort, length of hospitalisation and return to work/school and social life. Weinvestigated the effect of liposomal bupivacaine (LB) and aloe vera 2% cream (AVC) on post-haemorrhoidectomy pain and wound healing.Method: We established four treatment groups: G1, G2, G3 and G4. Then, we applied perianal submucosal 300 mg LB to 20 patients in G1intraoperatively; perianal 300 mg LB + local AVC to 20 patients in G2, 3 times a day, postoperatively; perianal AVC to 20 patients in G3 3 times a day,postoperatively and perianal placebo cream to 32 patients in G4 3 times a day, postoperatively. Patients’ pain at rest at the 12th, 24th and 36th hours andthe during defaecation at the 36th hour were scored using the visual analogue scale, “0” indicating “no pain” and “10” indicating “unbearable pain”.We recorded their needs for narcotic analgesics within postoperative 12 and 24 hours and for NSAID within 36 hours, as well as their return to sociallife and work and full recovery periods.Results: The difference was significant between the following groups: G1-G4 (p=0.042) & G2-G4 (p=0.002) in the need for narcotic analgesicswithin the first 24 hours, G2-G4 (p=0.002) in pain score at the 12th hour, G2-G4 (p<0.001) in pain score at the 24th hour, G2-G4 (p<0.001) & G3-G4(p=0.001) in pain score at the 36th hour, G2-G4 (p<0.001) in pain score during defaecation at the 36th hour and G2-G4 (p<0.001) in the return towork and social life.Conclusion: We recommend the combined use of LB and AVC after haemorrhoidectomy.