The relation of trauma type on the levels of plasma c-reactive protein in patients with post-traumatic stress disorder Travma sonrası stres bozukluğu hastalarında travma tipinin plazma C-reaktif protein düzeyi ile ilişkisi


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Olam N., Yaşar A. B.

Anadolu Psikiyatri Dergisi, cilt.20, sa.6, ss.573-580, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5455/apd.37158
  • Dergi Adı: Anadolu Psikiyatri Dergisi
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.573-580
  • Anahtar Kelimeler: CRP, Inflammation, Posttraumatic stress disorder, Trauma type
  • İstanbul Gelişim Üniversitesi Adresli: Evet

Özet

Objective: Studies investigating the relationship between posttraumatic stress disorder (PTSD) that is chronic psychiatric disorder and C-reactive protein (CRP) level have inconsistent results. However, to our knowledge, there is no study investigating the effect of PTSD-related trauma type on plasma CRP levels. This study was planned to determine the effect of PTSD and PTSD-related trauma type on plasma CRP levels. Methods: The sample of this cross-sectional study consisted of 73 PTSD patients and 69 healthy control subjects. After proper blood collection, Clinician-Administered PTSD Scale (CAPS) was administered by the researchers and Sociodemographic Data Form, Beck Depression Inventory (BDI) and Dissociative Experiences Scale (DES) were requested. Results: CRP, BDI and DES scores of PTSD patients were statistically higher than healthy controls. There were statistically significant differences between plasma CRP level, CAPS and DES scores according to different trauma types. In the comparison of bilateral groups, plasma CRP levels of occupational accident-induced PTSD patients were statistically higher than patients with PTSD due to other types of trauma. Conclusion: As a result, there were differences in plasma CRP levels between PTSD patients and healthy control group and plasma CRP levels were found to vary with the type of trauma associated with PTSD. (Anatolian Journal of Psychiatry 2019; 20(6):573-580).