Efficacy of intragastric balloon placement and botulinum toxin injection in bariatric endoscopy

Kanlioz M., Ekici U., Tatli F., KARATAŞ T.

Surgical Laparoscopy, Endoscopy and Percutaneous Techniques, vol.30, no.6, pp.500-503, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 6
  • Publication Date: 2020
  • Doi Number: 10.1097/sle.0000000000000829
  • Journal Name: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.500-503
  • Keywords: Bariatric endoscopy, Body mass index, Gastric balloon, Gastric botulinum toxin, Obesity and obesity treatment
  • Istanbul Gelisim University Affiliated: Yes


© 2020 Wolters Kluwer Health, Inc. All rights reserved.Background:To evaluate the results obtained from the combination of intragastric botulinum toxin A (IGBTA), intragastric balloon (IGB), and IGBTA(+)IGB in the treatment of obesity.Materials and Methods:Three separate treatment groups were set up. IGBTA, IGB, and IGBTA(+)IGB were administered to Group 1, 2, and 3, respectively. The body mass indexes (BMI) of patients were measured before and 6 months after the treatment. The intragroup and intergroup treatment results have been evaluated. P<0.05 was considered significant.Results:The mean BMI decreased by 1.6 kg/m2 in 40 patients who received IGBTA in group 1 (P<0.001), 3.95 kg/m2 in 42 patients who received IGB in group 2 (P<0.001), and 4.9 kg/m2 in 39 patients who received IGBTA and IGB in group 3 (P<0.001) after 6 months of treatment. The intolerance because of the application was the highest in group 3, followed by group 2.Conclusion:The treatment was most successful in group 3 followed by group 2 and group 1, respectively. The authors recommend the group 3 treatment, provided that nausea, vomiting, and flatulence have a high index of probability in such a treatment. However, when deciding between group 1 and group 2 treatments, the authors recommend opting for group 2 treatment that shows to be more efficient.