Akademik Veri Yönetim Sistemi
Ergonomics International Journal (EOIJ), cilt.8, sa.1, ss.322-329, 2024 (Hakemli Dergi)
The current magnetic-based biosensor technologies are expensive and intricate, making them unsuitable for meeting the
requirements of point-of-care medical diagnosis. This research introduces a straightforward magnetic biosensor architecture
that includes an L-shaped ferromagnetic core with UL dimensions. The design involves an air gap being replaced with highly
porous aluminum or copper foam, offering a potentially cost-effective and uncomplicated solution for point-of-care diagnosis
based on the magnetic field effect. The foam serves as a medium for hosting biological samples, such as proteins and DNA,
which are labeled with high-permeability ferromagnetic nanoparticles. The biosensor operates by detecting labeled biological
molecules through magnetic field interactions. The electrical parameters of the system underwent methodical optimization
to enhance overall performance. The investigation delved into the influence of various materials on the magnetic properties
of the air gap. It also examined the relationships between permeability, output-induced voltage, input voltage, and input
frequency. The findings reveal that utilizing materials with elevated magnetic permeability, such as Magnetite (Fe3
O4
) or
Cobalt ferrite (CoFe2
O4
) ferrofluids, significantly enhances the biosensor's performance by optimizing magnetic coupling
between primary and secondary windings. This innovative magnetic biosensor exhibits potential applications in diverse fields,
including molecular biology and medical diagnostics. The study contributes valuable insights into the design and optimization
of magnetic biosensors, offering opportunities for heightened sensitivity and selectivity in the detection of ferromagnetic
nanoparticles labeled biomolecules such as DNA or proteins.