Application of ultrasound to the organic cornelian cherry (Cornus mas L.) vinegar: Changes in antibacterial, antidiabetic, antihypertensive, and anticancer activities
Journal of Food Processing and Preservation, cilt.46, sa.11, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 11
- Basım Tarihi: 2022
- Doi Numarası: 10.1111/jfpp.16952
- Dergi Adı: Journal of Food Processing and Preservation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aquatic Science & Fisheries Abstracts (ASFA), Biotechnology Research Abstracts, Business Source Elite, Business Source Premier, CAB Abstracts, Compendex, Food Science & Technology Abstracts, INSPEC, Veterinary Science Database
- İstanbul Gelişim Üniversitesi Adresli: Hayır
Özet
In this study, to determine their alternative/complementary properties, organic cornelian cherry vinegar samples prepared by traditional (CCV), thermal pasteurization (P-CCV), and ultrasound (UT-CCV) methods were tested for antibacterial, antidiabetic, antihypertensive, and anticancer activities. As a result of response surface methodology optimization, the bioactive compounds were increased. With ultrasound treatment, the total phenolic content increased by 4.6%. The antibacterial activity was detected in all samples, while the lowest MIC values (28.4 μl/ml) in the presence of UT-CCV were found in Pseudomonas aeruginosa, Klebsiella pneumoniae, Bacillus cereus, and Staphylococcus aureus. In addition, apoptosis was induced in HT-29 and MDA-MB-231 cells were treated with the CCV, P-CCV, and UT-CCV samples compared to the control group. It was determined that UT-CCV has antidiabetic and antihypertensive effects. Therefore, our study encourages further clinical research on the alternative/complementary property of cornelian cherry vinegar in the treatment of various health manifestations including infections, cancer, diabetes, and hypertension. Novelty Impact Statement: Bioactive components of organic cornelian cherry vinegar increased with ultrasound treatment. Organic cornelian cherry vinegar stimulates apoptosis in cancer cells. Vinegar samples prepared by the UT-CCV method show better antibacterial activity compared to CCV and P-CCV samples.