Akademik Veri Yönetim Sistemi
9. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi, Ankara, Türkiye, 18 - 19 Mart 2022, ss.115-116
Introduction: Metabolic (dysfunction)-associated fatty liver disease (MAFLD), one of the major health problems of the 21st century, is associated with several metabolic dysfunctions. In the literature, it has been shown that cornelian cherry (Cornus mas L., CM) fruit rich in polyphenols, especially anthocyanin, can improve MAFLD. The aim of this study was to evaluate the effect of adding lyophilised CM fruit to the diets of MAFLD patients on anthropometric measurements and biochemical parameters. Method: The study was conducted on 28 patients with MAFLD in a private University Hospital in Istanbul. Participants were randomly divided into groups with and without lyophilised CM fruit (30 g/day) added to their diets for 8 weeks. Results: In lyophilised CM fruit group, body weight (p: 0.003), BMI (p: 0.003), body fat mass (p: 0.003), and waist and hip circumference (p: 0.003 and p: 0.013) were decreased compared to at the end of 8 weeks. Additionally, there was a statistically decrease in fasting blood glucose (p: 0.002), fasting insulin (p: 0.001), HOMA-IR (p: 0.001), HbA1c (p: 0.002), AST (p: 0.012), ALT (p: 0.019), ALP (p: 0.006), GGT (p: 0.007), total triglyceride (p: 0.002) and LDL cholesterol (p: 0.011) levels in this group. Conclusion: Regular consumption of lyophilised CM can improve MAFLD symptoms. Further studies are needed to support these results.