Objective: This study is to demonstrate the reliability and validity of the Turkish form of Panic Disorder Scale developed according to DSM-5 criteria to measure the severity of panic disorder. Methods: This study was carried out with patients with a diagnosis of any anxiety disorder according to DSM-5 criteria who are under treatment in Celal Bayar University Faculty of Medicine Psychiatry Inpatient or Outpatient Clinics. Patients with any mental or physical disease except for anxiety disorders were excluded. Accordingly, 50 patients with anxiety disorder were included in the study and these were distributed as panic disorder in 14 patients, generalized anxiety disorder in 10 patients, agoraphobia and obsessive-compulsive disorder in four patients, post-traumatic stress disorder in one patient and not otherwise specified anxiety disorder in 18 patients. As the healthy control group 103 volunteers without any mental or physical disease were included. Beside Panic Disorder Scale the most widely used self-rated scale, Spielberger’s State-Trait Anxiety Inventory was used for concurrent validity. In reliability analysis internal consistency coefficient and item-total correlation analysis; in validity analyses factor analysis and correlation analysis with the Spearman Correlation Analysis (SCA) was performed for validation. Results: The mean age of the study group was 29.0±11.8 years and 60.1% of the sample group (n=92) were female. 66.0% of the group were college graduates, 19.0% primary school graduates, 15.0% is also high school graduates. Disease duration of anxiety disorder group was 17.1±9.7 years. The internal consistency coefficient of the Panic Disorder Scale was 0.96 and, item-total correlation coefficients of the Panic Disorder Scale were between 0.68 and 0.88.In the exploratory factor analysis, for sample adequacy Kaiser-Meier-Olkin (KMO) coefficient was calculated as 0.92 and Bartlett coefficient was 1.57. Single-factor solution was obtained and the eigenvalue was 7.38, explaining 73.8% of the total variance. Factor loadings of the items were between 0.73 and 0.91. Coefficient of correlation analysis with SCA was calculated as r=0.32. Conclusion: These findings have been shown that the Panic Disorder Scale is reliable and valid for Turkish.