Evaluation of cognitive functions in individuals with synthetic cannabinoid use disorder and comparison to individuals with cannabis use disorder


Cengel H., Bozkurt M., Evren C., Umut G., Keskinkilic C., Agachanli R.

Psychiatry Research, vol.262, pp.46-54, 2018 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 262
  • Publication Date: 2018
  • Doi Number: 10.1016/j.psychres.2018.01.046
  • Journal Name: Psychiatry Research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.46-54
  • Keywords: Cannabis, Cognitive functions, Spice, Synthetic cannabinoid
  • Istanbul Gelisim University Affiliated: No

Abstract

The use of synthetic cannabinoid has been increasing throughout the world and has become a major public health problem. The present study aims to investigate the attention, memory, visuospatial and executive functions in individuals with synthetic cannabinoid use disorder and compare the results with findings obtained from individuals with cannabis use disorder and healthy volunteers with no substance use. Fifty-two patients with synthetic cannabinoid use disorder, 45 patients with cannabis use disorder and 48 healthy control group males were included in the study. The neuropsychological test battery was designed to involve ten studies evaluating a large series of cognitive functions. Impairments in attention, memory, executive and visuospatial functions were identified in individuals with synthetic cannabinoid use disorder and these impairments were found to be significantly greater than in individuals with cannabis use disorder and healthy controls. In line with the data obtained from this study; the evaluation of each cognitive function with more comprehensive test batteries and supporting these evaluations with sensitive brain imaging studies are important topics for future research.